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Researchers hope this breakthrough will help serve as a strong foundation for future heart studies.'Uncovering barriers that stand in the way of heart cells' self-healing process brings us another step closer to finding a cure for one of the world's biggest killers', said Dr Ng Huck Hui director of the Genome Institute of Singapore.Two types of omega-3 fatty acid found in oily fish – EPA and DHA – and the omega-6 fat arachidonic acid were linked to a lower risk of heart disease.
He said yesterday: ‘This huge and important study provides even more evidence that our focus purely on saturated fat as the number one dietary villain in causing heart disease has been misplaced when we should be focusing on food groups.
A mouse heart cell with 2 nuclei (blue) and Singheart RNA labelled by red fluorescent dyes.
Unlike most other cells in the human body, heart cells do not have the ability to self-repair effectively, making heart attack and heart failure severe and debilitating This novel RNA, which researchers have named 'Singheart,' may be targeted for treating heart failure in the future.
But omega-3 and omega-6 supplements appeared to have no benefit.
Lead researcher Dr Rajiv Chowdhury, from Cambridge University, said: ‘These are interesting results that potentially stimulate new lines of scientific inquiry and encourage careful reappraisal of our current nutritional guidelines.‘Cardiovascular disease, in which the principal manifestation is coronary heart disease, remains the single leading cause of death and disability worldwide.